Norgine and European Liver Patients Association (ELPA) Announce Publication That Advances the Understanding of Hepatic Encephalopathy

LONDON, May 3, 2016 /PRNewswire/ --

Norgine B.V. and ELPA today announced that they have achieved a significant milestone by publishing Hepatic encephalopathy: a call to action to optimize patient outcomes in Digestive and Liver Disease. This publication advances the understanding of hepatic encephalopathy and highlights the need to raise awareness of hepatic encephalopathy among the public and to improve the quality of care for patients.[1]

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De Gottardi A, et al. Hepatic encephalopathy: A call to action to optimize patient outcomes. Dig Liver Dis (2016),

The publication highlights the Time to DeLiver: Getting a Grip on HE campaign that aims to drive change in the management of hepatic encephalopathy. It calls for the inclusion of hepatic encephalopathy within public-facing information, improvements in the diagnosis and treatment of hepatic encephalopathy, the provision of quality of care for patients, and that the patient's voice should be heard on a national and European level. The barriers to the effective management of patients with hepatic encephalopathy were identified and 10 'calls to action' were developed for healthcare systems to address these barriers.

Tatjana Reic, President, ELPA commented "This publication challenges the need to further understand hepatic encephalopathy and most importantly will help increase national health care systems understanding of this debilitating disease. Hopefully this will bring us a step closer to ensure that patients receive more effective care and treatments."

Hepatic encephalopathy is a potentially life-threatening neuropsychiatric condition associated with liver disease. Hepatic encephalopathy affects approximately 200,000 people in Europe who suffer from advanced chronic liver disease.[2],[3] Hepatic encephalopathy remains underdiagnosed and under-treated, resulting in poor quality of life for patients and high burden on their carers, families and society.

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1. De Gottardi A, et al. Hepatic encephalopathy: A call to action to optimize patient outcomes. Dig Liver Dis (2016),

2. Blachier M et al, EASL Burden of Liver Disease in Europe, 2013

3. Amodio P et al, J Hepatol, 35 (2001) 37-45, 2001

Media Contacts:

Isabelle Jouin, T: +44(0)1895-453643 
Charlotte Andrews, T: +44(0)1895-453607 
Follow us @Norgine 
Thomas Szekely, M: +32-2-880-4349 
Follow us @HepatitisEurope 



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