CORK, Ireland, February 23, 2016 /PRNewswire/ --
Intramuscular 2-drug maintenance therapy demonstrates comparable antiviral activity to
daily oral 3-drug combination
Janssen Sciences Ireland UC, one of the Janssen Pharmaceutical Companies of Johnson & Johnson, (Janssen) announced 32-week data from an ongoing phase IIb study. A regimen of two investigational long acting, intramuscular (IM) formulations of HIV medicines-Janssen's rilpivirine and ViiV Healthcare's cabotegravir-given together every 4 or 8 weeks-show comparable antiviral activity to 3-drug oral antiretroviral therapy (ART) (investigational cabotegravir and two nucleoside reverse transcriptase inhibitors (NRTIs). The full results of the study, named LATTE-2, co-funded by Janssen and ViiV Healthcare were presented at this year's Conference on Retroviruses and Opportunistic Infections (CROI) in Boston, Massachusetts today.
(Logo: http://photos.prnewswire.com/prnh/20160223/336306LOGO )
The LATTE-2 study is investigating the safety and efficacy of 2-drug IM ART, relative to 3-drug oral ART when used to maintain viral suppression in HIV-1 infected adults.
Virologic responses (plasma HIV-1 RNA