STOCKHOLM, Sweden, September 16, 2015 /PRNewswire/ --
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Findings from a head-to-head trial comparing Victoza(R) (liraglutide) and lixisenatide, both in combination with metformin, demonstrated a significantly greater reduction in HbA1c of -1.83% for liraglutide vs -1.21% for lixisenatide in adults with type 2 diabetes.Results from the LIRA-LIXI trial were announced today in an oral presentation at the 51st Annual Meeting of the European Association for the Study of Diabetes (EASD) in Stockholm, Sweden.
The 26-week LIRA-LIXI trial compared the efficacy and safety of Victoza(R) versus lixisenatide, both as add-on to metformin in 404 people with type 2 diabetes. People with type 2 diabetes treated with Victoza(R) achieved a significantly greater reduction in HbA1c versus lixisenatide at 26 weeks, meeting the trial's primary endpoint (-1.83% vs -1.21%; estimated treatment difference [ETD] -0.62% [-0.80; -0.44]; P